Mechanical Circulatory Support in Patients Without Cardiogenic Shock Undergoing Percutaneous Coronary Intervention

• DOI: 10.1161/jaha.124.037424
• Publication Date: 2025-01-10T11:18:19Z
• Authors: P. Elliott Miller; Aliza S. Gordon; Ying Liu; Tariq Ahmad; Samantha G. Bromf...; Saket Girotra; Carlos D. Davila; Geoffrey Crawford; John Whitney; Nihar R. Desai
• Keywords: mechanical circulatory support; RC666-701; high‐risk PCI; acute myocardial infarction; Diseases of the circulatory (Cardiovascular) system

The use of mechanical circulatory support devices for high-risk percutaneous coronary intervention (PCI) has increased over the past decade despite limited data benefit. We sought to examine association between intravascular microaxial left ventricular assist device (LVAD) versus intra-aortic balloon pump in patients without cardiogenic shock (CS) undergoing PCI. This retrospective study analyzed claims from a large, insured population who underwent PCI CS April 1, 2016 July 31, 2022. Using inverse probability treatment weighting, we assessed type and clinical outcomes. primary outcome was all-cause mortality. Secondary outcomes included stroke, bleeding, incident dialysis, repeat revascularization, total health care costs during index admission at 30 days. identified 2879 with either an or LVAD. mean±SD age 68.2±12.5 years, 27% (n=764) were women. After propensity LVAD not associated significant difference in-hospital (odds ratio [OR] 1.30 [95% CI, 0.88-1.91]; In PCI, higher but lower Randomized are needed improve selection