Risk of Stroke and Myocardial Infarction After Reduction or Cessation of Cigarette Smoking

• DOI: 10.1161/strokeaha.107.512632
• Publication Date: 2008-07-11T01:38:22Z
• Authors: Yun-Mi Song; Hong-Jun Cho
• Keywords: Stroke

Background and Purpose— The effect of smoking reduction on cardiovascular disease outcomes has not been studied in Asian populations. Methods— A total 475 734 Korean men aged 30 to 58 years, stratified into 9 groups based status at 2 different time points (1990 1992), were followed from 1992 2001 for the occurrence stroke or myocardial infarction (MI) events. Results— Compared with nonreducing heavy smokers (≥20 cigarettes/d), those who quit showed significantly lower risks ischemic stroke, subarachnoid hemorrhage, MI hazard ratios (95% confidence intervals [CI]) 0.66 (0.55 0.79), 0.58 (0.38 0.90), 0.43 (0.34 0.53), respectively. For hemorrhagic quitters risk compared smokers, but difference was statistically significant (hazard ratio 0.82, 95% CI: 0.64 1.06). all combined among reducers tended decrease, although reductions significant. hemorrhage reduced moderate light be than (10 19 cigarettes/d) smokers. association between level did change when analysis limited whose maintained up 1994. Conclusions— Smoking cessation associated a decrease MI. More studies are needed verify likely health benefits reducing smoking.