Cerebral Aneurysm Sac Growth as the Etiology of Recurrence After Successful Coil Embolization

• DOI: 10.1161/strokeaha.111.637827
• Publication Date: 2011-12-16T06:55:35Z
• Authors: David M. Hasan; Alexander I. Nada...; Anna L. Hoppe; Kelly B. Mahaney; David K. Kung; Madhavan L. Raghavan
• Keywords: Adult; Male; Anatomy, Cross-Sectional; Angiography, Digital Subtraction; Intracranial Aneurysm; Aneurysm, Ruptured; Middle Aged; Embolization, Therapeutic; Blood Vessel Prosthesis; Cerebral Angiography; 3. Good health; Young Adult; 03 medical and health sciences; Imaging, Three-Dimensional; 0302 clinical medicine; Recurrence; Image Processing, Computer-Assisted; Humans; Female; Aged

Coil compaction is thought to be the main mechanism for recurrence in cerebral aneurysms with previously successful coil embolization. We hypothesize that sac growth may equally or more important. The objective was study relative roles of and as explanations aneurysm requiring retreatment a population using quantitative 3D image processing methods.From July 2009 December 2010, 175 were coiled at University Iowa hospitals clinics. Eight had major (4.4-12.1 months between procedures; mean: 7.2 months). structures vessel mass reconstructed rotational angiography data scanned before after both initial embolization retreatment. Changes over time visualized model registration techniques quantified volume calculations.All 8 significant (15% 102% increase volume), independent change volume. Five sufficient assessment compaction. decreased 1 (12% by did not significantly (increased 1%), increased 3 (8%, 21%, 25%) first treatment second treatment.In this population, growth, compaction, primary associated