Longitudinal Phenotypes and Mortality in Preserved Ratio Impaired Spirometry in the COPDGene Study

• DOI: 10.1164/rccm.201804-0663oc
• Publication Date: 2018-06-06T20:04:20Z
• Authors: Emily S. Wan; Spyridon Fortis; Elizabeth A. Regan; John Hokanson; MeiLan K. Han; Richard Casaburi; Barry J. Make; James D. Crapo; Dawn L. DeMeo; Edwin K. Silverman; James D. Crapo; Edwin K. Silverman; Barry J. Make; Elizabeth A. Regan; Terri Beaty; Ferdouse Begum; Peter J. Castaldi; Michael Cho; Dawn L. DeMeo; Adel R. Boueiz; Marilyn G. Foreman; Eitan Halper-Stro...; Lystra P. Hayden; Craig P. Hersh; Jacqueline Hetmanski; Brian D. Hobbs; John E. Hokanson; Nan Laird; Christoph Lange; Sharon M. Lutz; Merry-Lynn McDonald; Margaret M. Parker; Dandi Qiao; Elizabeth A. Regan; Edwin K. Silverman; Emily S. Wan; Sungho Won; Phuwanat Sakornsa...; Dmitry Prokopenko; Mustafa Al Qaisi; Harvey O. Coxson; Teresa Gray; MeiLan K. Han; Eric A. Hoffman; Stephen Humphries; Francine L. Jacobson; Philip F. Judy; Ella A. Kazerooni; Alex Kluiber; David A. Lynch; John D. Newell; Elizabeth A. Regan; James C. Ross; Raul San Jose Est...; Joyce Schroeder; Jered Sieren; Douglas Stinson; Berend C. Stoel; Juerg Tschirren; Edwin Van Beek; Bram van Ginneken; Eva van Rikxoort; George Washko; Carla G. Wilson; Robert Jensen; Douglas Everett; Jim Crooks; Camille Moore; Matt Strand; Carla G. Wilson; John E. Hokanson; John Hughes; Gregory Kinney; Sharon M. Lutz; Katherine Pratte; Kendra A. Young; Surya Bhatt; Jessica Bon; MeiLan K. Han; Barry Make; Carlos Martinez; Susan Murray; Elizabeth Regan; Xavier Soler; Carla G. Wilson; Russell P. Bowler; Katerina Kechris; Farnoush Banaei-K...; Jeffrey L. Curtis; Carlos H. Martinez; Perry G. Pernicano; Nicola Hanania; Philip Alapat; Mustafa Atik; Venkata Bandi; Aladin Boriek; Kalpatha Guntupalli; Elizabeth Guy; Arun Nachiappan; Amit Parulekar; Dawn L. DeMeo; Craig Hersh; Francine L. Jacobson; George Washko; R. Graham Barr; John Austin; Belinda D’Souza; Gregory D. N. Pea...; Anna Rozenshtein; Byron Thomashow; Neil MacIntyre; H. Page McAdams; Lacey Washington; Charlene McEvoy; Joseph Tashjian; Robert Wise; Robert Brown; Nadia N. Hansel; Karen Horton; Allison Lambert; Nirupama Putcha; Richard Casaburi; Alessandra Adami; Matthew Budoff; Hans Fischer; Janos Porszasz; Harry Rossiter; William Stringer; Amir Sharafkhaneh; Charlie Lan; Christine Wendt; Brian Bell; Marilyn G. Foreman; Eugene Berkowitz; Gloria Westney; Russell Bowler; David A. Lynch; Richard Rosiello; David Pace; Gerard Criner; David Ciccolella; Francis Cordova; Chandra Dass; Gilbert D’Alonzo; Parag Desai; Michael Jacobs; Steven Kelsen; Victor Kim; A. James Mamary; Nathaniel Marchetti; Aditi Satti; Kartik Shenoy; Robert M. Steiner; Alex Swift; Irene Swift; Maria Elena Vega-...; Mark Dransfield; William Bailey; Surya Bhatt; Anand Iyer; Hrudaya Nath; J. Michael Wells; Joe Ramsdell; Paul Friedman; Xavier Soler; Andrew Yen; Alejandro P. Come...; Karin F. Hoth; John Newell; Brad Thompson; MeiLan K. Han; Ella Kazerooni; Carlos H. Martinez; Joanne Billings; Abbie Begnaud; Tadashi Allen; Frank Sciurba; Jessica Bon; Divay Chandra; Carl Fuhrman; Joel Weissfeld; Antonio Anzueto; Sandra Adams; Diego Maselli-Cac...; Mario E. Ruiz
• Keywords: Longitudinal Study

Increasing awareness of the prevalence and significance Preserved Ratio Impaired Spirometry (PRISm), alternatively known as restrictive or Global Initiative for Chronic Obstructive Lung Disease (GOLD)-unclassified spirometry, has expanded body knowledge on cross-sectional risk factors. However, longitudinal studies PRISm remain limited.