Bacterial Inhibition and Oxidative Stress Remedial Properties of Azadirachta indica and Moringa oleifera

• DOI: 10.1166/sam.2020.3764
• Publication Date: 2020-03-27T04:47:41Z
• Authors: Khursheed Ul Islam; Benazir Chishti; Atul Kulkarni; H. Fouad; Mohamed Hashem; H. K. Seo; Z. A. Ansari
• Keywords: Azadirachta; Moringa; Phytochemical; Decoction; Agar diffusion test

Bacterial resistance towards the use of synthetic drugs has created a havoc in modern era health sciences. Medicinal plants may pave way for alternative source medicines that can overcome bacterial resistance. In this regard, employing three different extraction procedure (Maceration, Decoction and Soxhlet) aqueous extract Moringa oleifera Azadirachta indica were prepared observed inhibition antioxidant properties. Phytochemical screening results revealed presence phenols, flavonoids, reducing sugars saponins. Percentage scavenging activity primarily DPPH assay shows Soxhlet 6th (MOS 6th) with highest percentage activity. Similarly, total flavonoid content estimation rendered (MOD) as containing sample (68.97 ± 0.9) mg RUE/ml. Antibacterial efficiency extracts was monitored against Streptococcus mutans (gram-positive) Escherichia coli ( E. Coli ) DH5 (gram-negative) bacteria, 96-well microtiter two-fold dilution reveals lowest MIC 625 μ g ml –1 Neem soxhlet cycle (NS while oliefera soxhelt 2nd low toxicity pattern (MIC 5000 ). However, only (Neem cycle, cycle) inhibitory potential . Furthermore, zone acquired via agar-well diffusion well corroborates pate. Based on procedure, method establishes good profile studied organism.