Computerized tomography and neuropsychological test measures in adolescents with obsessive-compulsive disorder

• DOI: 10.1176/ajp.141.3.363
• Publication Date: 2014-12-17T19:16:45Z
• Authors: David Béhar; Judith L. Rapoport; Carol J. Berg; Martha B. Denckla; Lee S. Mann; Christian W. Cox; Paul Fedio; Theodore P. Zahn; Mark G. Wolfman
• Keywords: Neuropsychological test; Neuropsychological Assessment; Frontal lobe; Neuropsychological testing; Tic disorder

The authors administered CAT scans and neuropsychological tests to 16 adolescents with obsessive-compulsive disorder (mean age +/- SD = 13.7 1.6 years) matched controls. patients had a mean ventricular-brain ratio (VBR) significantly higher than the controls' showed spatial-perceptual deficits similar those found in frontal lobe lesions. Memory, reaction time, decision time did not differ from controls'. Neurodevelopmental examination of seven yielded high frequency age-inappropriate synkinesias left hemibody signs. These results suggest CNS dysfunctioning children disorder, possible right cerebral involvement. However, patients' test VBRs were correlated.