Prospective Diagnosis of the Initial Prodrome for Schizophrenia Based on the Structured Interview for Prodromal Syndromes: Preliminary Evidence of Interrater Reliability and Predictive Validity

• DOI: 10.1176/appi.ajp.159.5.863
• Publication Date: 2002-10-11T18:20:39Z
• Authors: Tandy J. Miller; Thomas H. McGlashan; Joanna Lifshey Rosen; Lubna Somjee; Philip J. Markovich; Kelly Stein; Scott W. Woods
• Keywords: Prodrome; Inter-Rater Reliability; Validity; Face validity

OBJECTIVE: This study was conducted to determine the interrater reliability and predictive validity of a set diagnostic criteria for prodrome first episode schizophrenic psychosis when based on Structured Interview Prodromal Syndromes. METHOD: The subjects were patients referred evaluation because suspected schizophrenia prodromal syndrome. For study, two four raters independently diagnosed 18 basis face-to-face or videotaped interviews. 6- 12-month outcome data collected 29 patients. RESULTS: Agreement in differentiating from nonprodromal 93%. features had converted 46% at 6 months 54% 12 months. CONCLUSIONS: In small groups subjects, these Syndromes showed promising validity.