Relapse Prevention in Patients With Bipolar Disorder: Cognitive Therapy Outcome After 2 Years

• DOI: 10.1176/appi.ajp.162.2.324
• Publication Date: 2005-01-27T23:18:39Z
• Authors: Dominic H. Lam; Peter Hayward; Edward R. Watkins; Kim Wright; Pak Sham
• Keywords: Relapse prevention

OBJECTIVE: In a previous randomized controlled study, the authors reported significant beneficial effects of cognitive therapy for relapse prevention in bipolar disorder patients up to 1 year. This study reports additional 18-month follow-up data and presents an overview effect over 30 months. METHOD: Patients with DSM-IV I (N=103) suffering from frequent relapses were randomly assigned into plus medication group or control condition only. Independent raters, who blind patient status, assessed at 6-month intervals. RESULTS: Over months, had significantly better outcome terms time relapse. However, was mainly first The also spent 110 fewer days (95% CI=32 189) episodes out total 900 whole months 54 CI=3 105) 450 last 18 Multivariate analyses variance showed that exhibited mood ratings, social functioning, coping prodromes, dysfunctional goal attainment cognition. CONCLUSIONS: after compliance controlled. results no reduction period. Further studies should explore booster sessions maintenance therapy.