Treatment of Akinetic Mutism with Intramuscular Olanzapine: A Case Series

• DOI: 10.1176/jnp.2008.20.1.93
• Publication Date: 2014-12-17T21:42:32Z
• Authors: David R. Spiegel; Daniel P. Casella; David M. Callender; Neetu Dhadwal
• Keywords: Akinetic mutism

Akinetic mutism is a wakeful state of severe apathy and paucity volitional movement. Evidence indicates possible dopaminergic hypofunction within the anterior cingulate cortex. The authors present three cases acute onset akinetic successfully treated with intramuscular olanzapine.