Decreased serum bilirubin levels in children with lead poisoning

• DOI: 10.1177/0300060521990248
• Publication Date: 2021-02-09T08:14:53Z
• Authors: Mengsi Ye; Tingting Zhang; Zhibo Chen; Shuo Chen; Huale Chen
• Keywords: Serum Albumin

Objective Lead is a toxic heavy metal, which causes irreversible damage in children. Oxidative stress the underlying mechanism of lead toxicity, and monitoring oxidative poisoning children vivo important. Our study aimed to investigate blood serum levels biochemical parameters, including albumin, bilirubin, creatinine, uric acid, are regarded as non-enzymatic antioxidants, with poisoning. Methods We studied 355 age- sex-matched controls. analyzed clinical characteristics measured total protein, globulin, aspartate aminotransferase (AST), alanine aminotransferase, urea, creatinine. Results found that creatinine were significantly lower AST, globulin higher than Direct AST associated after adjustment for other covariates. Spearman analysis showed direct urea independent indicators (i.e., not related hemoglobin or weight), while moderate correlation weight. Conclusion interferes antioxidant system children, results decrease bilirubin levels.