Subacute Sclerosing Panencephalitis: Clinical and Magnetic Resonance Imaging Evaluation of 36 Patients

• DOI: 10.1177/088307380201700106
• Publication Date: 2008-03-31T22:40:10Z
• Authors: Aylin Öztürk; Candan Gürses; Betül Baykan; Ayşen Gökyiğit; Mefkure Eraksoy
• Keywords: Subacute sclerosing panencephalitis; Hemiparesis

We studied 36 patients (24 males, 12 females), all of whom had definite subacute sclerosing panencephalitis with typical periodic complexes in their electroencephalograms and increased titers measles antibody serum cerebrospinal fluid. Their clinical laboratory findings on admission were reviewed retrospectively. The age at onset symptoms varied from 4 to 23 years. average disease was 13.1 +/- 4.18 mean the duration infection 9 Unusual symptoms, especially early periods disease, included hemiparesis (7 patients), headache (3), generalized tonic-clonic seizures (6), absence seizure (1), nausea vomiting (3). Twenty-six cranial magnetic resonance imaging (MRI) computed tomography examinations performed. Nine normal MRI. In stages, lesions usually involved parieto-occipital corticosubcortical regions asymmetrically. time, symmetric periventricular white-matter changes became more prominent. addition common cases reported literature, there some different features disease. Eventually, we concluded that seems be no correlation between stages either or MRI findings.