Non-invasively measured central and peripheral factors of oxygen uptake differ between patients with chronic heart failure and healthy controls

• DOI: 10.1186/s12872-020-01661-4
• Publication Date: 2020-08-18T12:03:21Z
• Authors: Joana Brochhagen; Michael Thomas Co...; Christian Baumgart; Jürgen Freiwald; Matthias Wilhelm ...
• Keywords: Angiology; Vascular surgery

Maximum oxygen uptake is an established measurement of diagnosing chronic heart failure and underlies various central peripheral factors. However, factors are little investigated, because they usually measured invasively. The aim this study was to compare non-invasively between patients with healthy controls.Ten male reduced ejection fraction (62 ± 4 years; body mass index: 27.7 1.8 kg/m2; fraction: 30 4%) ten controls (59 3 1.3 kg/m2) were tested for blood pressure, rate, stroke volume, cardiac output, power output (central factors) as well muscle saturation the vastus lateralis biceps brachii (peripheral during incremental cycling test. Stroke volume by a bioreactance analysis near-infrared spectroscopy, respectively. Additionally, maximum isometric strength test knee extensors conducted. Magnitude-based inferences computed statistical analyses.Patients had likely most lower uptake, mean arterial rate at load very peak torque. Contrary, possibly higher load. Differences in unclear.Non-invasively differ controls. Therefore, it promising measure both types optimize diagnosis therapy.