Minimal important difference and patient acceptable symptom state for the Numerical Rating Scale (NRS) for pain and the Patient-Rated Wrist/Hand Evaluation (PRWHE) for patients with osteoarthritis at the base of thumb

• DOI: 10.1186/s12874-022-01600-1
• Publication Date: 2022-04-29T06:04:56Z
• Authors: Susanna Stjernber...; Teemu Karjalainen; Joona Juurakko; Pirjo Toivonen; Eero Waris; Simo Taimela; Clare L. Ardern; Teppo L. N. Järvinen; Jarkko Jokihaara
• Keywords: Wrist pain

Abstract Background The Numerical Rating Scale (NRS) and Patient-rated wrist/hand evaluation (PRWHE) are patient-reported outcomes frequently used for evaluating pain function of the wrist hand. aim this study was to determine thresholds minimal important difference (MID) patient acceptable symptom state (PASS) NRS PRWHE instruments in patients with base thumb osteoarthritis. Methods Fifty-two symptomatic osteoarthritis wore a splint six weeks before undergoing trapeziectomy. (0 10) 100) were collected at time recruitment (baseline), after immobilization prior surgery, 3, 6, 9 12 months surgery. Four anchor-based methods MID PRWHE: receiver operating characteristics (ROC) curve, mean change (MDC), (MC) predictive modelling methods. Two approaches PASS 75 th percentile ROC curve anchor question perceived by compared baseline; whether would be satisfied if condition stay similar. correlation between transition baseline outcome all points combined calculated using Spearman’s rho analysis. Results 2.5 method, 2.0 MDC 2.8 MC method. corresponding MIDs 22, 24, 10, 20. values 30 22 75th respectively. area under (AUC) analyses showed excellent discrimination measures. Conclusion We found credible estimates (including its subscales), although varied depending on method used. 20-30% range scores instruments. cut-offs good or discrimination, lending support their use future studies. Trial registration This clinimetrics approved Helsinki University ethical review board (HUS1525/2017).