Association between the cardiometabolic index and non-alcoholic fatty liver disease: insights from a general population

• DOI: 10.1186/s12876-022-02099-y
• Publication Date: 2022-01-12T17:02:53Z
• Authors: Jiawang Zou; Hailan Xiong; Huimin Zhang; Chong Hu; Song Lu; Yang Zou
• Keywords: Male; 0303 health sciences; Adolescent; Research; Cholesterol, HDL; Cardiometabolic index; General population; RC799-869; Diseases of the digestive system. Gastroenterology; Middle Aged; 3. Good health; 03 medical and health sciences; CMI; Cardiovascular Diseases; Non-alcoholic Fatty Liver Disease; Risk Factors; NAFLD; Humans; Female; Triglycerides; Non-alcoholic fatty liver disease; Aged

Emerging evidence suggests that cardiometabolic index (CMI) is closely related to diabetes, hypertension, stroke, cardiovascular disease, and kidney which implies CMI has the value as an indicator of metabolic diseases. However, data on relationships between non-alcoholic fatty liver disease (NAFLD) risks have not been reported. This study designed examine association NAFLD in general population.The current included 14,251 subjects whose was product triglyceride/high-density lipoprotein cholesterol ratio waist-to-height ratio. Linear regression used analyze correlation baseline information CMI, logistic relationship NAFLD, subgroup analysis explore potential high-risk groups.After adjusted for confounding factors, higher independently associated with every additional standard deviation (SD) increased risk by 28% (OR 1.28 per SD increase, 95% CI 1.19-1.37, P trend < 0.0001). There were also significant differences CMI-related among different ages genders, young people significantly than other age groups = 2.63 increase people, OR 1.38 middle-aged 1.18 elderly people; 1.14 interaction 0.0010), women men 1.58 women, 1.26 men, 0.0045).Current studies found after excluding population risk.