Infection with high proportion of multidrug-resistant bacteria in conflict-related injuries is associated with poor outcomes and excess resource consumption: a cohort study of Syrian patients treated in Jordan

• DOI: 10.1186/s12879-018-3149-y
• Publication Date: 2018-05-22T07:54:49Z
• Authors: Andreas Älgå; Sidney Wong; Muhammad Shoaib; Kalle Lundgren; Christian G. Giske; Johan von Schreeb; Jonas Malmstedt
• Keywords: Medical microbiology; Tropical Medicine; Wound infection

Armed conflicts are a major contributor to injury and death globally. Conflict-related injuries associated with high risk of wound infection, but it is unknown what extent infection directly relates sustainment life restoration function. The aim this study was investigate the outcome resource consumption among civilians receiving acute surgical treatment due conflict-related injuries. Patients without infections were compared. We performed cohort using routinely collected data from 457 consecutive Syrian that received for during 2014–2016 at Jordanian hospital supported by Médecins Sans Frontières. defined as clinical signs verified positive culture. used logistic regression models evaluate infection-related differences in consumption. Wound 49/457 (11%) patients. Multidrug-resistance (MDR) detected 36/49 (73%) patients infection. Among 11/49 (22%) amputated, compared 37/408 (9%) crude relative = 2.62 (95% confidence interval 1.42–4.81). Infected needed 12 surgeries on average, five non-infected (p < .00001). Mean length stay 77 days 35 .000001). civilians, infected wounds had prevalence MDR bacteria. poor outcomes These results could guide development antibiotic protocols adaptations management improve care ClinicalTrials.gov ( NCT02744144 ). Registered April 13, 2016. Retrospectively registered.