Annual and seasonal patterns in etiologies of pediatric community-acquired pneumonia due to respiratory viruses and Mycoplasma pneumoniae requiring hospitalization in South Korea

• DOI: 10.1186/s12879-020-4810-9
• Publication Date: 2020-02-12T14:02:47Z
• Authors: Eun Lee; Chul-Hong Kim; Yong Ju Lee; Hyo-Bin Kim; Bong-Seong Kim; Hyung Young Kim; Yunsun Kim; Sangyoung Kim; Chorong Park; Ju-Hee Seo; In Suk Sol; Myongsoon Sung; Min Seob Song; Dae Jin Song; Young Min Ahn; Hea Lin Oh; Jinho Yu; Sungsu Jung; Kyung Suk Lee; Ju Suk Lee; Gwang Cheon Jang; Yoon-Young Jang; Eun Hee Chung; Hai Lee Chung; Sung-Min Choi; Yun Jung Choi; Man Yong Han; Jung Yeon Shim; Jin Tack Kim; Chang-Keun Kim; Hyeon-Jong Yang
• Keywords: Etiology; Mycoplasma pneumonia; Medical microbiology

Abstract Background Community–acquired pneumonia (CAP) is one of the leading worldwide causes childhood morbidity and mortality. Its disease burden varies by age etiology time dependent. We aimed to investigate annual seasonal patterns in etiologies pediatric CAP requiring hospitalization. Methods conducted a retrospective study 30,994 children (aged 0–18 years) with between 2010 2015 at 23 nationwide hospitals South Korea. Mycoplasma pneumoniae (MP) was clinically classified as macrolide-sensitive MP, macrolide-less effective MP (MLEP), macrolide-refractory (MRMP) based on fever duration after initiation macrolide treatment, regardless results vitro sensitivity tests. Results respiratory syncytial virus (RSV) were two most commonly identified pathogens CAP. With epidemics (2011 2015), rates clinical MLEP MRMP showed increasing trends 36.4% total pneumonia. In < 2 years age, RSV (34.0%) common cause CAP, followed (9.4%); however, aged 2–18 (45.3%). Systemic corticosteroid administered for The rate hospitalization intensive care units highest pneumonia, ventilator needed cases adenovirus Conclusions present provides fundamental data establish public health policies decrease due improve health.