Hepatitis E seroprevalence and risk factors in humans and pig in Ghana

• DOI: 10.1186/s12879-022-07127-6
• Publication Date: 2022-02-07T14:04:14Z
• Authors: Husein Bagulo; Ayodele O. Majeko...; Susan C. Welburn; Langbong Bimi
• Keywords: Seroprevalence; Parasitology; Medical microbiology; Tropical Medicine

Although Hepatitis E virus (HEV) infection has significant negative impact on the health and wellbeing of underprivileged populations, burden HEV in Ghana is still unclear, despite widespread water, sanitation, hygiene (WASH) related conditions that predispose people to risk infection.A cross-sectional study was conducted explore rates seroprevalence prevalence, as well factors humans domestic pigs Ghana. These were determined using ELISAs manufactured by Wantai Beijing Biopharmaceuticals, China. The involved 1365 community members, 105 pig farmers 474 from four administrative regions Ghana.Results showed overall prevalence 12.4% 0.7% members 15.2% 2.9% respectively. There no difference between two groups (Z = 0.851; p 0.3953). However, significantly higher than 2.412; 0.016). Age (OR 1.369, CI 1.243 - 1.508; 0.0000), gender 1.419, 1.101 1.991; 0.043), region residence 1.569, 1.348 1.827; 0.0000) for a multivariate regression model. In pigs, 62.4% 5.5% recorded A found confined (6.7%) free-range (88.3%), 7.492; < 0.00001) Volta Region. Multivariate logistic association husbandry 7.051, 3.558- 13.972; 4.602, 2.300 9.205; Greater Accra Region.From this study, endemic with high populations. This underscores need awareness creation action prevention control.