Efficacy of ultrasonography and Tc-99m MIBI SPECT/CT in preoperative localization of parathyroid adenomas causing primary hyperthyroidism

• DOI: 10.1186/s12880-021-00616-1
• Publication Date: 2021-05-21T08:03:04Z
• Authors: Ruigang Lu; Wei Zhao; Li Yin; Ruijun Guo; Bojun Wei; Mulan Jin; Xiang Zhou; Chun Zhang; Xiuzhang Lv
• Keywords: Parathyroid neoplasm; Parathyroid gland

Primary hyperparathyroidism (PHPT) results from an excess of parathyroid hormone (PTH) produced overactive gland. The study aimed to explore the sonographic features adenomas and assess diagnostic performance ultrasonography (US) Tc-99m MIBI SPECT/CT for preoperative localization adenomas.A total 107 patients were enrolled in this retrospective who had PHPT underwent parathyroidectomy. Of patients, 97 performed US examinations nodules. sensitivity accuracy each modality calculated.In study, residual sign polar vascular identified as characteristic adenomas. These manifestations closely related size abnormal lesions. Among 108 nodules with PHPT, locating significantly higher than those (93.0% vs. 63.0% 88.0% respectively; χ2 = 26.224, 18.227 respectively, P < 0.001). differences between + SPECT/CT-alone statistically significant (χ2 33.410, 21.587 0.001), yet there no or US-alone 0.866, 0.187 0.352 0.665).US shows better SPECT/CT. However, combined is great clinical value PHPT.