Association between extracellular volume control and survival in patients on short daily haemodialysis

• DOI: 10.1186/s12882-020-01821-w
• Publication Date: 2020-04-29T19:03:17Z
• Authors: Ana Beatriz Lesqu...; Ana Paula Roque-d...; Marcos S. Vasconc...; Jocemir R. Lugon; Jorge Paulo Strog...
• Keywords: SDHD; Nephrology

Abstract Background Fluid overload (FO) assessed by bioimpedance spectroscopy (BIS) is associated with higher mortality risk in maintenance haemodialysis (HD). The aim was to assess if a better management of FO through short daily (SDHD) could improve survival. Methods Retrospective analysis patients who were on HD 3 sessions/week for at least months and shifted in-centre SDHD (5 or 6 sessions/week, 2 h/session) between July 2012 June 2016 23 dialysis units Brazil. 12-month death analysed according the predialysis hydration status measured before after initiation SDHD. Predialysis considered adequate when ≤15% extracellular volume. Results A total 297 included analysis. Their median age 57 (IQR 45–67) years, 62% males, 44% diabetics, 57% session duration 130 120–150) minutes. BIS assessment regimen performed 220 > 15% found 46.4%. Twelve-month survival rates those ≤15 initiating 87.4 88.0%, respectively ( P = 0.92). completing available 229 patients, 26.6% 15%. next 12 (from 6th 18th month follow-up) 91.0 72.0%, 0.0006). In Cox regression model, adjustment demographic, clinical laboratory variables, ≤ persisted lower (hazard ratio 0.34, 95%CI 0.13–0.87). Conclusions Moving from conventional control excessive Patients reached maintained fluid presented death.