Accuracy of axial length, keratometry, and refractive measurement with Myopia Master in children with ametropia

• DOI: 10.1186/s12886-022-02672-9
• Publication Date: 2022-12-03T11:02:49Z
• Authors: Yuhao Ye; Yu Zhao; Tian Han; Xiaoyu Zhang; Huamao Miao; Bing Qin; Xingtao Zhou
• Keywords: Male; Adolescent; Research; RE1-994; Refractive Errors; Axial length; Ophthalmology; 03 medical and health sciences; Myopia Master; Ametropia; Cross-Sectional Studies; 0302 clinical medicine; Child, Preschool; Myopia; Humans; Female; Prospective Studies; Child; Physical Examination; Keratometry

Abstract Purpose To evaluate the accuracy of axial length, keratometry, and refractive measurement with Myopia Master in ametropic children.

Methods In this randomized prospective cross-sectional study, 125 children with ametropia (250 eyes) were recruited (55 boys and 70 girls; age range: 3–15 years). All examinations were performed under full cycloplegic conditions. Measurements of axial length (AL), keratometry, and autorefraction acquired with the Myopia Master were compared with those from the IOLMaster 500, IOLMaster 700, Nidek ARK-1, and manifest refraction. The differences between the different methods were analyzed, and their correlation was assessed by interclass correlation coefficients (ICCs), Bland–Altman plot, and correlation test.

Results The ALs (mm) measured with Myopia Master, IOLMaster 500, and IOLMaster 700 were 23.67 ± 1.26, 23.68 ± 1.26, and 23.70 ± 1.25, respectively. The mean values and standard deviations for AL and keratometry readings from these devices were similar (P ≥ 0.059). The ICC analysis also revealed high consistency between the measurements (ICC ≥ 0.943). Additionally, the correlation coefficients were relatively high (r > 0.9, p < 0.001). Although the results of refraction obtained with the Myopia Master were slightly higher than those with manifest refraction (P ≤ 0.024), the agreement between these two measurements was excellent (ICC ≥ 0.858). The percentage of points outside the limits of agreements was < 5.22% in Bland–Altman plots for all analyses.

Conclusions Myopia Master could be a highly efficient tool for clinical use as a three-in-one system (AL, keratometry, and refractive measurements) for screening in children with ametropia.