The impact of moderate to severe osteoarthritis on the physical performance and quality of life: a cross-sectional study in Greek patients (PONOS study)

• DOI: 10.1186/s12891-023-06770-7
• Publication Date: 2023-08-15T07:01:53Z
• Authors: P. Savvari; I. Skiadas; S. A. Papadakis; V. Psychogios; O. D. Argyropoulou; A. P. Pastroudis; G. A. Skarpas; A. Tsoutsanis; A. Garofalakis; G. Katsifis; D. Boumpas; D. Menegas
• Keywords: Cross-sectional study; Sports medicine

Abstract Background Osteoarthritis (OA) represents a leading cause of disability with limited data available for the Greek patients. Objectives To evaluate impact moderate to severe symptomatic hip/knee OA under treatment on physical performance and quality life. Methods A non-interventional, cross-sectional, epidemiological study patients moderate/severe OA, recruited in single visit from 9 expert sites Athens, Greece. Assessments were based commonly used outcome scales: Hip Outcome Score (HOOS), Knee Injury (KOOS) EuroQol-5-Dimensions 3-levels questionnaire (EQ-5D-3L). Results One hundred sixty-four included analysis. Most females (78.7%), mean age 70.5 ± 10.2 years. Comorbidities reported by 87.2% hypertension being most frequently (53.7%), followed dyslipidemia (31.1%), obesity (24.4%) diabetes mellitus (23.2%). Paracetamol was common (96%), NSAIDs (75%), opioids (50%) locally applied medications (42.7%). Both hip knee showed substantial deterioration health-related life (QoL) health status as reflected HOOS/KOOS (Function sport recreation impaired subscale, Hip- or Knee-related QoL). The EQ-5D-3L index score 0.396 0.319 EQ-VAS 52.1 1.9. When compared indirectly local population norms our had worse QoL indices. Conclusion Our findings suggest functional emphasizing need novel treatments that will reduce burden disease.