Relationships between obesity and prevalence of gout in patients with type 2 diabetes mellitus: a cross-sectional population-based study

• DOI: 10.1186/s12902-024-01672-8
• Publication Date: 2024-08-02T03:46:46Z
• Authors: Ningyu Cai; Mengdie Chen; Ping Feng; Qidong Zheng; Xianping Zhu; Suqing Yang; Zhaobo Zhang; Yiyun Wang
• Keywords: Cross-sectional study

The purpose of this study was to investigate the relationships between generalized, abdominal, and visceral fat obesity prevalence gout in patients with type 2 diabetes mellitus (T2DM). Data were obtained from electronic medical databases National Metabolic Management Center (MMC) Yuhuan Second People's Hospital Taizhou Central (Taizhou University Hospital) September 2017 June 2023. Four indicators analyzed: waist circumference (WC), waist-to-hip ratio (WHR), body mass index (BMI), area (VFA). these parameters analyzed using multivariate logistic regression restricted cubic spline (RCS) analyses. Receiver operating characteristic (ROC) curves used evaluate diagnostic efficacy four for gout. This cross-sectional enrolled 10,535 participants (600 cases 9,935 controls). Obesity more common gout, markedly higher group. After adjustment confounders, obesity, as defined by BMI, WC, WHR, VFA, found be associated greater prevalence, odds ratios (OR) 1.775, 1.691, 1.858, 1.578, respectively (P < 0.001). increased relation indicator quartiles (P-value trend 0.001), positively correlated shown RCS. under ROC curve values VFA 0.629, 0.651, 0.634, 0.633, respectively. Obesity—whether general, or obesity—was linked elevated risk. But uncovering causality behind relationship requires further prospective study. (BMI, VFA) may have potential value diagnosing clinical practice.