The investigation of Helicobacter pylori in the dental biofilm and saliva samples of children with dyspeptic complaints

• DOI: 10.1186/s12903-017-0361-x
• Publication Date: 2017-03-21T20:24:30Z
• Authors: Damla Aksit Bıcak; Serap Akyuz; Binnur Kıratlı; Merve Usta; Nafiye Urganci; Burcin Alev; Aysen Yarat; Fikrettin Sahin
• Keywords: Dental plaque

The oral cavity can be an extra-gastric reservoir for Helicobacter pylori (H.pylori). This play a role in the pathogenesis of halitosis, glossitis, recurrent aphthous stomatitis, and dental caries. present study was conducted to detect presence H.pylori within biofilm saliva samples collected from children suffering dyspepsia without any gastrointestinal complaints. Associations with gastric infection, some parameters were also evaluated. Seventy (aged between 5–16) selected group control composed 30 healthy included study. After detailed clinical examinations parameters, saliva, supragingival 16S rRNA 23S genes detection by real-time polymerase chain reaction (RT-PCR). evaluated endoscopic biopsy specimens histopathologically. Halitosis benzoyl-DL-arginine-naphthylamid (BANA) test. Salivary S.mutans Lactobacilli sp. counts carried out commercial kits. histopathologically detected amongst 83% dyspeptic condition. rate this bacteria halitosis found relatively higher rather than (p < 0.01). not significantly different those > 0.05). In positive dyspepsia, DMFT/S dmft/s numbers plaque indices Only negative groups Comparing both genes, whose results DMFS lower dmfs pH values occur aside independently stomach. However, high number cavities H.pylori, association DMFS, found.