Effect of dental intervention on improvements in metabolic syndrome patients: a randomized controlled clinical trial

• DOI: 10.1186/s12903-020-01373-3
• Publication Date: 2021-01-06T21:03:31Z
• Authors: Midori Doke; Yuriko Komagamine; Manabu Kanazawa; Maiko Iwaki; Hiroyuki Suzuki; Yasunari Miyazaki; Tetsuya Mizuno; Kaori Okayasu; Shunsuke Minakuchi
• Keywords: Metabolic Syndrome; RK1-715; Periodontal treatment; Metabolic syndrome; Body Mass Index; Diet; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Dentistry; Humans; Prosthodontic treatment; Obesity; Dental intervention; Waist Circumference; Life Style; Research Article

Abstract Background Metabolic syndrome (MetS), caused by the accumulation of visceral fat, is considered a major cause cardiovascular disease. This randomized controlled trial aimed to clarify effect dental intervention, including prosthodontics and/or periodontal treatment, combined with dietary and exercise guidance on MetS. Methods In total, 112 patients who met Japanese waist circumference criteria MetS were recruited. The intervention group (ITG) received along guidance, while control (CTG) alone. Three outcome measurements obtained before (BL), 1 month after (1M), 3 months (3M). Results Body water rate ( p = 0.043) was significantly higher in ITG than CTG at 1M. Simultaneously, fasting blood sugar level 0.098) tended be lower CTG. Lean mass 0.037) muscle 0.035) body weight 0.044) 3M. index 0.052) Conclusions Dental lifestyle may improve anthropometric status reduce risk Trial registration University Hospital Medical Information Network Center Unique UMIN000022753. https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000026176 .