Uptake and correlates of cervical cancer screening among women attending a community-based multi-disease health campaign in Kenya

• DOI: 10.1186/s12905-022-01702-4
• Publication Date: 2022-04-18T10:12:05Z
• Authors: Yujung Choi; Saduma Ibrahim; Lawrence P. Park; Craig R. Cohen; Elizabeth A. Bukusi; Megan J. Huchko
• Keywords: Male; Uterine Cervical Neoplasms; HIV Infections; Cervical Cancer; 0302 clinical medicine; 5. Gender equality; Pregnancy; Mass Screening; Papillomaviridae; Early Detection of Cancer; Cancer; 360; screening and diagnosis; Public health; Health Services; 3. Good health; Detection; Infectious Diseases; Public Health and Health Services; HIV/AIDS; Female; Public Health; 4.4 Population screening; Public aspects of medicine; RA1-1270; Infection; 610; Nursing; Health Promotion; Midwifery; Paediatrics and Reproductive Medicine; 03 medical and health sciences; Clinical Research; Health Services and Systems; Health Sciences; Behavioral and Social Science; Humans; Obstetrics & Reproductive Medicine; Biomedical and Clinical Sciences; Prevention; Research; Papillomavirus Infections; Gynecology and obstetrics; Kenya; Good Health and Well Being; Cross-Sectional Studies; Reproductive Medicine; Cost Effectiveness Research; RG1-991; Sexually Transmitted Infections; Reproductive medicine

Abstract Introduction Despite the increased risk of cervical cancer among HIV-positive women, many HIV-care programs do not offer integrated cervical cancer screening. Incorporating self-collected Human Papillomavirus (HPV) testing into HIV programs is a potential strategy to identify women at higher risk for cervical cancer while leveraging the staffing, infrastructure and referral systems for existing services. Community-based HIV and HPV testing has been effective and efficient when offered in single-disease settings.

Methods This cross-sectional study was conducted within a community outreach and multi-disease screening campaigns organized by the Family AIDS Care and Education Services in Kisumu County, Kenya. In addition to HIV testing, the campaigns provided screening for TB, malaria, hypertension, diabetes, and referrals for voluntary medical male circumcision. After these services, women aged 25–65 were offered self-collected HPV testing. Rates and predictors of cervical cancer screening uptake and of HPV positivity were analyzed using tabular analysis and Fisher’s Exact Test. Logistic regression was performed to explore multivariate associations with screening uptake.

Results Among the 2016 women of screening age who attended the outreach campaigns, 749 women (35.6%) were screened, and 134 women (18.7%) were HPV-positive. In bivariate analysis, women who had no children (p < 0.01), who were not pregnant (p < 0.01), who were using contraceptives (p < 0.01), who had sex without using condoms (p < 0.05), and who were encouraged by a family member other than their spouse (p < 0.01), were more likely to undergo screening. On multivariable analysis, characteristics associated with higher screening uptake included: women aged 45–54 (OR 1.62, 95% CI 1.05–2.52) compared to women aged 25–34; no children (OR 1.65, 95% CI 1.06–2.56); and family support other than their spouse (OR 1.53, 95% CI 1.09–2.16). Women who were pregnant were 0.44 times (95% CI 0.25–0.76) less likely to get screened. Bivariate analyses with participant characteristics and HPV positivity found that women who screened HPV-positive were more likely to be HIV-positive (p < 0.001) and single (p < 0.001).

Conclusions The low screening uptake may be attributed to implementation challenges including long waiting times for service at the campaign and delays in procuring HPV test kits. However, given the potential benefits of integrating HPV testing into HIV outreach campaigns, these challenges should be examined to develop more effective multi-disease outreach interventions.