Ultrasound guided double injection of blood into cisterna magna: a rabbit model for treatment of cerebral vasospasm

• DOI: 10.1186/s12938-016-0123-z
• Publication Date: 2016-02-06T11:24:30Z
• Authors: Yongchao Chen; Youzhi Zhu; Yu Zhang; Zixuan Zhang; Juan Lian; Fucheng Luo; Xuefei Deng; Kelvin KL Wong
• Keywords: Cisterna magna; Cerebral Vasospasm; Rabbit (cipher); Cisterna

Double injection of blood into cisterna magna using a rabbit model results in cerebral vasospasm. An unacceptably high mortality rate tends to limit the application model. Ultrasound guided puncture can provide real-time imaging guidance for operation. The aim this paper is establish safe and effective vasospasm after subarachnoid hemorrhage with assistance ultrasound medical imaging. A total 160 New Zealand white rabbits were randomly divided four groups 40 each: (1) manual control group, (2) (3) (4) group. was intentionally caused by double their magna. Then, basilar artery diameters measured magnetic resonance angiography before modeling 5 days modeling. depth needle entering determined during process puncture. rates group 15 23 %, respectively. No sacrificed those two groups. We found that decreased significantly compared Compared modeling, lower aggravated proportion severe vasospasms greater than In no 8 % rabbits. treatment