A clinical role of staging laparoscopy in patients with radiographically defined locally advanced pancreatic ductal adenocarcinoma

• DOI: 10.1186/s12957-016-0767-y
• Publication Date: 2016-01-20T15:11:39Z
• Authors: Sohei Satoi; Hiroaki Yanagimoto; Tomohisa Yamamoto; Hideyoshi Toyokawa; Satoshi Hirooka; So Yamaki; Singh Sapam Opendro; Kentaro Inoue; Taku Michiura; Hironori Ryota; Yoichi Matsui; Masanori Kon
• Keywords: Surgical oncology

The aim of current study is to verify usefulness staging laparoscopy (stag-lap) for patient's selection and find prognostic factors in patients with radiographically defined locally advanced (RD-LA) pancreatic ductal adenocarcinoma (PDAC).The LA disease was as an unresectable without distant organ metastasis based on resectability status NCCN guideline this study. Stag-lap performed 67 RD-LA (2007-2012) which were divided into 4 groups according metastatic site: group CY (peritoneal fluid or washing cytology positive any metastasis); P dissemination); L (liver negative metastasis). Clinical backgrounds, survival curves, investigated.There 16 (24%), 13 (19%), 10 (15%), 28 (42%). Median time months 11 group, significantly better than 7 respectively (p<0.05). rate emergence ascites Multivariate analysis showed that the presence partial response administration second-line chemotherapy independent factors.The majority PDAC had occult metastasis. features curves different depending site Administration responsiveness associated favorable prognosis. Staging should be routinely (UMIN000019936).