Investigating the impact of SARS-CoV-2 infection on basic semen parameters and in vitro fertilization/intracytoplasmic sperm injection outcomes: a retrospective cohort study

• DOI: 10.1186/s12958-022-00918-1
• Publication Date: 2022-03-08T07:02:44Z
• Authors: Meng Wang; Juan Hu; Bo Huang; Qiyu Yang; Sibo Liu; Zhou Li; Liu Yang; Qingsong Xi; Lixia Zhu; Lei Jin
• Keywords: Semen quality

This study aimed to evaluate the influences of SARS-CoV-2 infection on semen parameters and investigate impact in vitro fertilization (IVF) outcomes.This retrospective enrolled couples undergoing IVF cycles between May 2020 February 2021 at Tongji Hospital, Wuhan. Baseline characteristics were matched using propensity score matching. Participants categorized into an unexposed group (SARS-COV-2 negative) exposed positive) based a history infection, populations 148 50 after matching, respectively. data compared cohorts. Moreover, before among infected males. The main measures outcomes, including laboratory clinical outcomes.Generally, concentration motility sperm did not significantly differ infection. Infected males seemed have fewer with normal morphology, while all values above limits. Notably, blastocyst formation rate available lower than those control group, despite similar mature oocytes rates, cleavage high-quality embryo rates. no significant differences exhibited cohorts regarding implantation rate, biochemical pregnancy or early miscarriage rate.The results this cohort suggested that quality chance terms outcomes comparable controls, although decreased was observed which needs be reinforced by multicenter long-term investigation larger sample size.