Assessment of cardiovascular risk factors in people with HIV infection treated with ART in rural South Africa: a cross sectional study

• DOI: 10.1186/s12981-015-0083-6
• Publication Date: 2015-12-13T04:51:47Z
• Authors: Felistas Mashinya; Marianne Alberts; Jean-Pierre Van g...; Robert Colebunders
• Keywords: Cross-sectional study; Stepwise regression

The risk of cardiovascular diseases (CVD) in human immunodeficiency virus (HIV) infected people on antiretroviral therapy (ART) from some rural parts Africa is not well known. We assessed CVD factors, the estimated 5-year Data collection adverse effects anti-HIV drugs (DA.) score and 10-year Framingham persons with HIV infection ART a area South Africa. A cross-sectional study which data demographic, lifestyle, chronic disease were collected using World Health Organization Stepwise approach to surveillance questionnaire. Biochemical parameters tested standard biochemical methods. CD4 counts performed PIMA analyser viral load was branched deoxyribonucleic acid technique. Student t test Chi square used continuous categorical variables respectively. Bivariate multivariate logistic regression analyze predictors factors. Estimates 5 calculated online tools. Cohen's kappa coefficient assess agreement between equations. mean age participants 44.8 ± 11.8 years; 79.9 % females. Most (85 %) had an undetectable count 462 235 cell/mm3. most common factors low high density lipoprotein cholesterol (HDL-C) (43.8 %), hypercholesterolaemia (33.2 Apolipoprotein (Apo) B/ApoA ratio (45.4 %).Using equation, 6.7 moderate while DAD equation showed that 31.1 risk. by both level two equations 73.8 (k = 0.23; 95 CI 0.10–0.35; p value 0.001). among this population ART. proportion risk, observed clearly represents considerable health burden can possibly be reduced increasing educational programs prevention for There however need develop evaluate race/ethnicity-specific estimation tool Africans.