Ringed fluorodeoxyglucose uptake predicted poor prognosis after resection of pulmonary pleomorphic carcinoma

• DOI: 10.1186/s13019-022-01799-6
• Publication Date: 2022-03-21T11:03:04Z
• Authors: Yutaka Shishido; Akihiro Aoyama; Shigeo Hara; Yuki Sato; Keisuke Tomii; Hiroshi Hamakawa; Yutaka Takahashi
• Keywords: Univariate analysis; Cardiothoracic surgery; Fluorodeoxyglucose

Pulmonary pleomorphic carcinoma (PPC) is a relatively rare and poorly differentiated non-small cell carcinoma. This study aimed to investigate the clinicopathological features including programmed death ligand 1 (PD-L1) expression status in patients with PPC who underwent curative resection.We retrospectively studied 29 consecutive had undergone anatomical lung resections for PPC. Perioperative pathological variables, radiological findings, were investigated define prognostic factors.Overall survival (OS) rates 71.8% at year 60.0% 5 years. Disease-free (DFS) 54.8% 43.6% Univariate analysis revealed that ringed fluorodeoxyglucose (FDG) uptake on positron emission tomography/computed tomography (PET/CT) (p = 0.003), cavity tumor CT 0.004), size (> 40 mm) 0.014) poor factors OS. Regarding DFS, FDG 0.002), < 0.001), 0.007), pleural invasion factors. PD-L1 was not factor.This showed first time PET/CT factor of related prognosis. Trial registration The approved by Kobe City Medical Center General Hospital's ethics board (No. 20112) August 20, 2020.