Evaluation of natural porcine circovirus type 2 (PCV2) subclinical infection and seroconversion dynamics in piglets vaccinated at different ages

• DOI: 10.1186/s13567-016-0405-2
• Publication Date: 2016-12-02T21:09:16Z
• Authors: Salvador Oliver-F...; Joaquim Segalés; Sergio López-Soria; Antonio Callén; Olivier Merdy; François Joisel; Marina Sibila
• Keywords: Seroconversion; Subclinical infection; Circovirus

This study aimed to determine the porcine circovirus type 2 (PCV2) serological and virological dynamics in piglets vaccinated at different ages a PCV2 subclinical infection (PCV2-SI) scenario. Six hundred forty-four week-old healthy were selected distributed into four treatment groups: vaccination 3, 6 or 10 weeks of age (3W-VAC, 6W-VAC 10W-VAC groups, respectively) unvaccinated pigs (NON-VAC group). Blood (n = 112 pigs) oral fluid (OF) 40 pens) samples taken throughout assess load, humoral immunity viral genotyping. Percentage PCV2-DNA positive sera mainly raised by age, being maximum 14 then started decrease 18 25 age. Specifically, 3 yielded similar results, since they produced an earlier seroconversion reduced, sampling points, proportion viremic animals comparison group. In contrast, only achieved such reduction age; this case, coincided with increase percentage population. Both techniques used OF offered results high statistically significant correlation. higher DNA positivity was detected sera. conclusion, under present conditions, optimal time for piglet either