The role of co-infections in M. hyopneumoniae outbreaks among heavy fattening pigs: a field study

• DOI: 10.1186/s13567-022-01061-w
• Publication Date: 2022-06-13T03:29:56Z
• Authors: Matteo Tonni; Nicoletta Formenti; M. Beatrice Boniotti; Flavia Guarneri; Federico Scali; Claudia Romeo; Paolo Pasquali; Maria Pieters; Dominiek Maes; Giovanni L. Alborali
• Keywords: Mycoplasma hyopneumoniae; Enzootic; Actinobacillus pleuropneumoniae; Atypical pneumonia

Abstract Little is known about how co-infections and genotype dynamics affect Mycoplasma hyopneumoniae infection in fattening pigs. This study was aimed at assessing the role of M. outbreaks, their influence on presence genotypes impact consequent lung lesions. Tracheobronchial swabs (TBS) from 300 finishers were collected 10 farms onset enzootic pneumonia outbreaks 1 month later, sampling 3 groups per farm: Group A showed clinical signs first, B housed near A, C located a different building. Pigs’ lungs scored slaughterhouse. TBS tested for main pathogens involved respiratory diseases, samples positive genotyped by multiple-locus variable-number tandem repeat analysis (MLVA). Pigs highest prevalence load . association detected between hyorhinis , whereas Actinobacillus pleuropneumoniae more frequent when higher. Nevertheless, co-infection had no effect lesion scores. The multiple MLVA types (mixed infections) increased time only pigs positively associated with porcine reproductive syndrome virus infection. Lung lesions severe least one history mixed infections. central relevance infections suggest that biosecurity might be beneficial sequelae.