Characteristics and outcome of COVID-19 patients admitted to the ICU: a nationwide cohort study on the comparison between the first and the consecutive upsurges of the second wave of the COVID-19 pandemic in the Netherlands

• DOI: 10.1186/s13613-021-00978-3
• Publication Date: 2022-01-13T06:08:49Z
• Authors: Dave A. Dongelmans; Fabian Termorshuizen; Sylvia Brinkman; Ferishta Bakhshi-...; M. Sesmu Arbous; Dylan W. de Lange; Bas C. T. van Bussel; Nicolette F. de K...; ; Dirk P Verbiest; Leo F te Velde; Erik M van Driel; Tom Rijpstra; Paul W. G. Elbers; Lyuba Georgieva; Eva Verweij; Remko M de Jong; Freya M van Iersel; Dick T. J. J. Koning; Els Rengers; Nuray Kusadasi; Michiel L Erkamp; Roy van den Berg; Cretièn J. M. G. ...; Jelle L Epker; Annemiek A Rijkeboer; Martha T de Bruin; Peter Spronk; Annelies Draisma; Dirk Jan Versluis; Lettie A. E. van ...; Marissa Vrolijk-d...; Judith A Lens; D Jannet Mehagnou...; Diederik Gommers; Johan G Lutisan; Martijn Hoeksema; Ralph V Pruijsten; Hans Kieft; Jan Rozendaal; Fleur Nooteboom; Dirk P Boer; Inge T. A. Janssen; Laura van Gulik; M Peter Koetsier; Vera M Silderhuis; Ronny M Schnabel; Ioana Drogt; Wouter de Ruijter; Rob J Bosman; Tim Frenzel; Louise C Urlings-...; Allard Dijkhuizen; Ilanit Z Hené; Arthur R de Meijer; Jessica W. M. Hol...; Nynke Postma; Alexander J. G. H...; Ronald M. J. Wess...; Eline R van Slobb...; Peter H. J. van d...; Bob J. W. Eikemans; Michel G. W. Barnas; Barbara Festen-Sp...; Maarten van Lieshout; Niels C Gritters; Martijn van Telli...; Gert B Brunnekreef; Joyce Vandeputte; Tom P. J. Dormans; Marga E Hoogendoorn; Mart de Graaff; David Moolenaar; Auke C Reidinga; Jan Jaap Spijkstra; Ruud de Waal
• Keywords: Third wave

Abstract Background To assess trends in the quality of care for COVID-19 patients at ICU over course time Netherlands. Methods Data from National Intensive Care Evaluation (NICE)-registry all admitted to an Netherlands were used. Patient characteristics and indicators during first two upsurges (N = 4215: October 5, 2020–January 31, 2021) final upsurge second wave, called ‘third wave’ 4602: February 1, 2021–June 30, compared with those wave 2733, February–May 24, 2020). Results During third there less treated mechanical ventilation (58.1 58.2%) vasoactive drugs (48.0 44.7%) (79.1% 67.2%, respectively). The occupancy rates as fraction 2019 (1.68 1.55 vs. 1.83), numbers relocations (23.8 27.6 32.3%) mean length stay (HRs discharge 1.26 1.42) lower wave. No difference adjusted hospital mortality between was found, whereas considerably (OR 0.80, 95% CI [0.71–0.90]). Conclusions These data show favorable shifts treatment time. decreased high rate early pandemic does probably not explain associated COVID-19.