Probiotic Pediococcus pentosaceus restored gossypol-induced intestinal barrier injury by increasing propionate content in Nile tilapia

• DOI: 10.1186/s40104-024-01011-w
• Publication Date: 2024-04-07T00:02:04Z
• Authors: Feifei Ding; Nannan Zhou; Yuan Luo; Tong Wang; Weijie Li; Fang Qiao; Zhenyu Du; Meiling Zhang
• Keywords: Nile tilapia; Gossypol; Cottonseed meal

Intestinal barrier is a dynamic interface between the body and ingested food components, however, dietary components or xenobiotics could compromise intestinal integrity, causing health risks to host. Gossypol, toxic component in cottonseed meal (CSM), caused injury fish other monogastric animals. It has been demonstrated that probiotics administration benefits but efficacy of maintaining when host exposed gossypol remains unclear. Here, strain (YC) affiliated Pediococcus pentosaceus was isolated from gut Nile tilapia (Oreochromis niloticus) its potential repair gossypol-induced damage evaluated.