RHOF promotes Snail1 lactylation by enhancing PKM2-mediated glycolysis to induce pancreatic cancer cell endothelial–mesenchymal transition

• DOI: 10.1186/s40170-024-00362-2
• Publication Date: 2024-10-26T10:01:57Z
• Authors: Rui Zhao; Yanmin Yi; Han Liu; Jianwei Xu; Shuhai Chen; Dong Wu; Lei Wang; Feng Li
• Keywords: PKM2

The influence of the small Rho GTPase Rif (RHOF) on tumor growth, glycolysis, endothelial-mesenchymal transition (EMT), and potential mechanism RHOF in pancreatic cancer (PC) were explored.