Combination of high-flow nasal oxygen and ketamine/dexmedetomidine sedation for diagnostic catheterization in a child with pulmonary arterial hypertension: a case report

• DOI: 10.1186/s40981-024-00699-z
• Publication Date: 2024-02-22T07:03:03Z
• Authors: Kaoru Tsuboi; Misuzu Asai; Toshiki Nakamura; Jun Ninagawa; Hiroshi Ono; Shugo Kasuya
• Keywords: Dexmedetomidine; Atelectasis; Cardiac catheterization; Positive airway pressure

Abstract Pulmonary hypertension is associated with significant risk of perioperative life-threatening events. We present a case 12-year-old child severe pulmonary arterial who successfully underwent diagnostic cardiac catheterization under ketamine and dexmedetomidine sedation the support high-flow nasal oxygen. Ketamine are reported to have minimal effect on vasculature in children can be safely used this population along its lack respiratory depression. Positive pressure generated by oxygen improves upper airway patency, prevents micro-atelectasis, shown improve effectiveness ventilation oxygenation patients breathing spontaneously. The presented strategy may contribute enhancing safety procedural for hypertension.