Duration of Adjuvant Doublet Chemotherapy (3 or 6 months) in Patients With High-Risk Stage II Colorectal Cancer

• DOI: 10.1200/jco.20.01330
• Publication Date: 2021-01-13T21:07:08Z
• Authors: Timothy J. Iveson; Alberto F. Sobrero; Takayuki Yoshino; Ioannis Souglakos; Fang-Shu Ou; Jeffrey P. Meyers; Qian Shi; Axel Grothey; Mark P. Saunders; Roberto Labianca; Takeharu Yamanaka; Ioannis Boukovinas; Niels H. Hollander; Fabio Galli; Kentaro Yamazaki; Vassilis Georgoulias; Rachel Kerr; Eiji Oki; Sara Lonardi; Andrea Harkin; Gerardo Rosati; James Paul
• Keywords: FOLFOX; Regimen; Clinical endpoint

As oxaliplatin results in cumulative neurotoxicity, reducing treatment duration without loss of efficacy would benefit patients and healthcare providers.