Prospective Study of the Correlation Between Postoperative Computed Tomography Scan and Primary Surgeon Assessment in Patients With Advanced Ovarian, Tubal, and Peritoneal Carcinoma Reported to Have Undergone Primary Surgical Cytoreduction to Residual Disease 1 cm or Less

• DOI: 10.1200/jco.2007.12.2317
• Publication Date: 2007-10-30T22:48:02Z
• Authors: Dennis S. Chi; Pedro T. Ramirez; Jerrold B. Teitcher; Svetlana Mironov; Debra M. Sarasohn; Revathy B. Iyer; Eric L. Eisenhauer; Nadeem R. Abu-Rustum; Yukio Sonoda; Douglas A. Levine; Carol L. Brown; Carol Aghajanian; David M. Gershenson; William J. Hoskins; Hedvig Hricak; Richard R. Barakat
• Keywords: Adult; Aged, 80 and over; Ovarian Neoplasms; Postoperative Care; Neoplasm, Residual; Middle Aged; 3. Good health; 03 medical and health sciences; Gynecologic Surgical Procedures; 0302 clinical medicine; Fallopian Tube Neoplasms; Humans; Female; Prospective Studies; Tomography, X-Ray Computed; Physical Examination; Peritoneal Neoplasms; Aged

Purpose To compare surgeons' operative assessments of residual disease (RD) to those identified on postoperative computed tomography (CT) scans in patients with advanced ovarian carcinoma reported have undergone optimal primary cytoreduction. Patients and Methods All at one two institutions, who were scheduled surgery for presumed cancer, asked consent a CT scan if cytoreduction ≤ 1 cm RD was reported. findings graded using qualitative analysis scale from (normal) 5 (definitely malignant). Results From January 2001 September 2006, 285 enrolled. A total 78 met eligibility criteria had scans. In 41 cases (52%), correlated the surgical report no more than cm, seven (9%), indeterminate. 10 (13%), noted by radiologist as probably malignant, 20 (26%), definitely malignant. these 30 cases, radiologically median largest mass 1.9 (range, 1.1 5.1), most commonly right upper quadrant (15 [50%]) central abdomen (nine [30%]). Conclusion There only 52% correlation between evaluations Further study is required determine whether this lack due rapid interval tumor regrowth, underestimated surgeons, and/or overestimated radiologists; clinical implications discrepancies.