Phase I study of RG7155, a novel anti-CSF1R antibody, in patients with advanced/metastatic solid tumors.

• DOI: 10.1200/jco.2015.33.15_suppl.3005
• Publication Date: 2019-03-07T22:17:57Z
• Authors: Carlos Alberto Go...; Philippe Alexandr...; Antoine Italiano; Michael Cannarile; Carola Ries; Anne Brillouet; Claudia Mueller; Anna-Maria Jegg; Georgina Meneses-...; Monika Baehner; Keelara Abiraj; Delphine Loirat; Maud Toulmonde; Sandra P. D'Angelo; Kristy Weber; Mario Campone; Dominik Ruettinger; Jean-Yves Blay; Jean-Pierre Delord; Christophe Le Tou...
• Keywords: 0301 basic medicine; 03 medical and health sciences; 3. Good health

3005 Background: Tumor associated macrophages (TAM) suppress anti-tumor immunity and have been associated with poor prognosis in several types of cancer. CSF-1 is a critical survival and differenti...