Risk factors predicting colorectal cancer recurrence in a Latin American population.

• DOI: 10.1200/jco.2019.37.15_suppl.e15180
• Publication Date: 2019-05-27T16:07:06Z
• Authors: Jorge Leon; Fernando Namuche; Paola Catherine M...; Claudio J. Flores
• Keywords: Univariate analysis; Log-rank test

e15180 Background: The incidence of colorectal cancer (CRC) in Peru has increased the last decades. In our population more than 80% patients are stage I-III. Recurrence is one most important factors to consider survival CRC patients. aim this study was identify which influence recurrence population. Methods: We retrospectively reviewed electronic medical records 506 with I-III from specialized Peruvian center between 2006 and 2016. Survival analysis (with as event evaluate) performed Kaplan Meier curves Long-rank test. use a preliminary univariate do multivariate Cox regression. ROC curve determine an appropriate cut-off value for tumor size (≥4.2). Results: we found that sidedness, (cut-off ≥4.2), CEA, lymph node involvement, stage, histological grade, LVI, PNI, chemotherapy were statistically significant. model, [HR, 1.462; 95% CI, 1.065-2.217; p<0.05], involvement 0.136; CI,0.41-0.447; p<0.001], III 0.003; 0.263-0.758; p<0.05] retained significant association independent relapse disease. Conclusions: pts it evaluate size, clinical they possible prognostic will help diagnosis treatment along other standard features.