Recruiting Black and White patients to a behavioral oncology clinical trial: Lessons from the DISCO trial.

• DOI: 10.1200/jco.2024.42.16_suppl.e13684
• Publication Date: 2024-05-29T17:43:22Z
• Authors: Lauren M. Hamel; Eyouab Tadesse; Roman Grossi; Lorna Mabunda; Teneisha Austin; David W. Dougherty; Keri Angers; Karis Tutuska; Mai Daigle; Susan Eggly
• Keywords: White (mutation); Clinical Oncology

e13684 Background: Clinical trials are often terminated due to insufficient accrual, with only about 6% of patients enrolling into a trial. Trial enrollment rates even lower for Black patients. In 2021, we began recruitment clinic-based behavioral trial testing the effectiveness health equity communication intervention designed address patient cancer treatment cost concerns. This study involves and providers completing surveys before after video-recorded clinical interaction. We implementing this at NCI-designated comprehensive center in Detroit, Michigan, city majority population. Based on findings that most agree participate if they eligible invited, set sample goal 50% White used evidence-based strategies lessons from our previous work, including having diverse staff building trusting relationships provider participants. As begin final year recruitment, consider what suggestions can offer teams seeking recruit trials. Methods: based evidence racially concordant (same racial group) dyads have better quality than discordant (different dyads, medical mistrust is greater among First, hired trained team includes members, encouraged them take leadership roles. Second, built trust providers, staff, Procedures involve discussing their recruiting as participants, screening eligibility. in-person clinic or by phone. Patients who provide oral consent later met person collect written consent. Results: achieved rate 52% across 4 clinics; 86 (61%) 55 (39%) patients, which reflects demographics attribute success critical aspects protocol. participants helps capture attention builds flexible approach. Once potential screened, approach Third, composition population hope recruit. Last, support group student members terms race, gender, age additional support. Conclusions: Our strategies, scientific literature, helped achieve diversity These similar be adapted other achieving equity. information: NCT04766190 .