Onset seizures independently predict poor outcome after subarachnoid hemorrhage

• DOI: 10.1212/wnl.55.9.1315
• Publication Date: 2012-05-13T13:49:29Z
• Authors: H. Butzkueven; A.H. Evans; A. Pitman; C. Leopold; D.J. Jolley; A.H. Kaye; C.J. Kilpatrick; S.M. Davis
• Keywords: Glasgow Outcome Scale

To determine whether onset seizures after subarachnoid hemorrhage (SAH) carry independent prognostic information and to investigate the risk factors for late SAH.Modern management of SAH, including early operation, has substantially reduced mortality. No study adequately assessed importance in a contemporary SAH cohort.The authors analyzed records initial CT scans 412 consecutive patients with aneurysmal or nonaneurysmal admitted Royal Melbourne Hospital from 1990 1996. Each patient an seizure (n = 32, 7.8% cohort) was age sex matched two nonseizure same cohort. 17, 5.1% five control subjects cohort.With use logistic regression analysis, correlated sum score blood on scan (OR 1.1, p 0.05), but there no significant correlation duration loss consciousness at onset, Glasgow Coma Score (GCS), presence aneurysm, past history hypertension epilepsy. Disability 6 weeks according Outcome Scale independently predicted by GCS <6 13.7, < 0.01) 7.8, 0.04). Late within first were related rebleeding 94, 27, not other variables, development hydrocephalus, vasospasm.In this single-institution cohort factor predictor poor outcome.