Forced Needle Advancement During Needle-Nerve Contact in a Porcine Model

• DOI: 10.1213/ane.0b013e31821b2227
• Publication Date: 2011-04-07T20:59:22Z
• Authors: Thorsten Steinfeldt; Sabine Poeschl; Wilhelm Nimphius; Juergen Graf; Martin Zoremba; Hans-Helge Mueller; Hinnerk Wulf; Frank Dette
• Keywords: Inflammation; Hematoma; Swine; Immunohistochemistry; 03 medical and health sciences; 0302 clinical medicine; Anesthesia, Conduction; Needles; Peripheral Nerve Injuries; Animals; Brachial Plexus; Peripheral Nerves; Myelin Sheath

In this study, we determined whether needle advancement during needle-nerve contact (forced needle-nerve contact) is associated with a higher risk of nerve injury compared with needle-nerve contact without needle advancement (nonforced needle-nerve contact).In 8 anesthetized pigs, the brachial plexus nerves underwent forced (0.15 Newton) or nonforced (0.0 Newton) needle-nerve contact without nerve penetration. The grade of nerve injury was histologically assessed using an objective score ranging from 0 (no injury) to 4 (severe injury).Sixty-nine nerves, including controls, were examined. Histology revealed a significant difference between forced and nonforced needle-nerve contact (median [interquartile range] 3 [2-4] vs 2 [1-2]; P = 0.004). Myelin damage and intraneural hematoma occurred only after forced needle-nerve contact.The severity of structural nerve injury after needle-nerve contact was directly related to force exposure via needle advancement.