Intraperitoneal Ropivacaine Nebulization for Pain Management After Laparoscopic Cholecystectomy

• DOI: 10.1213/ane.0b013e31822d447f
• Publication Date: 2011-10-04T22:46:18Z
• Authors: Mario Bucciero; Pablo M. Ingelmo; Roberto Fumagalli; Eric Noll; Andrea Garbagnati; Marta Somaini; Girish P. Joshi; Giovanni Vitale; Vittorio Giardini; Pierre Diemunsch
• Keywords: Ropivacaine

In Brief BACKGROUND: Studies evaluating intraperitoneal local anesthetic instillation for pain relief after laparoscopic procedures have reported conflicting results. this randomized, double-blind study we assessed the effects of nebulization on cholecystectomy. METHODS: Patients undergoing elective cholecystectomy were randomly assigned to receive either ropivacaine 0.5%, 20 mL induction pneumoperitoneum, or 1%, 3 before and surgery. Anesthetic surgical techniques standardized. Degree at rest deep breathing, incidence shoulder pain, morphine consumption, unassisted walking time, postoperative nausea vomiting evaluated 6, 24, 48 hours RESULTS: Of 60 patients included, exclusions occurred conversion open There no differences between groups in scores consumption. No group presented significant comparison with 83% (absolute risk reduction −83, 95% CI −97 −70, P < 0.001). Nineteen (70%) receiving walked without assistance within 12 surgery 14 (47%) −24, −48 1, = 0.04). One (3%) patient vomited 6 (22%) −19%, −36 −2, 0.03). CONCLUSIONS: Intraperitoneal was associated reduced time but an increased Published ahead print September 14, 2011