UNTREATED VESTIBULAR SCHWANNOMA

• DOI: 10.1227/01.neu.0000243285.06415.4c
• Publication Date: 2022-05-19T14:40:05Z
• Authors: Erling Myrseth; Per Møller; Tore Wentzel-Larsen; Frederik Goplen; Morten Lund-Johansen
• Keywords: Adult; Male; Health Status; Neuroma, Acoustic; Middle Aged; Prognosis; 3. Good health; Tinnitus; Case-Control Studies; Surveys and Questionnaires; Quality of Life; Vertigo; Humans; Female; Prospective Studies; Hearing Loss; Postural Balance; Aged

OBJECTIVE The aim of the present study was to characterise relation between quality life (QOL) and four major complaints (hearing loss, tinnitus, vertigo unsteadiness) caused by unilateral vestibular schwannoma (versus) in a cohort well-characterised untreated patients. METHODS One hundred ninety-nine consecutive patients (91 men, 108 women) with mean age 56.9 years were studied prospectively during 4-year period 2001–2004. average time span from symptom onset radiological diagnosis 4.2 years. subject standardised examination including MRI, evaluation hearing acuity, balance function stabilometry, visual analogue scale (VAS) self-evaluation tinnitus vertigo. Furthermore, responded two questionnaires, Short-Form 36 (SF-36) Glasgow Benefit Inventory (GBI)). A reference population recruited 80 adult persons who visited Haukeland University Hospital as non-patients or non-staff members. All data recorded customised case report form. Statistical analysis done SPSS software. RESULTS response rates Inventoryquestionnaires 91.5 89.9%, respectively. According SF-36 questionnaire scored significantly below that expected norms exception physical mental health. Patients negative benefit on general sections GBI questionnaire. Regression showed had strong impact QOL, whilst loss less QOL. CONCLUSION Vertigo is causing most pronounced effect QOL versus more frequent versus-symptoms seem be important patients' perception evaluated questionnaires used this study. If could relieved treatment, should focus when discussing treatment options small medium sized