Response of the Pacific oyster Crassostrea gigas, Thunberg 1793, to pesticide exposure under experimental conditions

• DOI: 10.1242/jeb.048033
• Publication Date: 2010-11-12T12:43:47Z
• Authors: H. Collin; A.-L. Meistertzheim; E. David; D. Moraga; I. Boutet
• Keywords: Pacific oyster; Shellfish Poisoning

SUMMARYPesticide run-off into the ocean represents a potential threat to marine organisms, especially bivalves living in coastal environments. However, little is known about effects of environmentally relevant concentrations pesticides at individual level. In this study, suppression subtractive hybridisation technique was used discover main physiological function affected by cocktail three (lindane, metolachlor and carbofuran) Pacific oyster Crassostrea gigas. Two populations exposed different pollution levels wild were investigated. The pesticide induce stress close those found wild. time course experiment, expression genes implicated iron metabolism oxidative as well that two ubiquitous proteins examined. No clear regulation gene or protein found, potentially due low-dose effect. we detected strong site- organ-specific response pesticides. This study thus (1) provides insight bivalve responses level transcriptome, which first for organisms facing pollution, (2) raises interesting questions concerning importance sites organs studied toxicogenomic field.