Exercise and 24-h Glycemic Control

• DOI: 10.1249/mss.0b013e31827ad8b4
• Publication Date: 2013-02-01T17:27:41Z
• Authors: JAN-WILLEM VAN DIJK; RALPH J. F. MANDERS; EMANUEL E. CANFORA; WILLEM VAN MECHELEN; FRED HARTGENS; COEN D. A. STEHOUWER; LUC J. C. VAN LOON
• Keywords: Crossover study

Purpose We assessed the effect of a single bout moderate-intensity exercise on subsequent 24-h glycemic control in 60 type 2 diabetes patients. Moreover, we examined whether individual responses to were related subjects’ baseline characteristics, including age, body mass index, duration, performance, medication, and HbA1c content. Methods Sixty patients (insulin-treated, n = 23) participated randomized crossover experiment. Patients studied two occasions for 3 d under strict dietary standardization but otherwise free-living conditions. Parameters (means [95% confidence interval]) by continuous glucose monitoring over period after endurance-type or no at all (control). Results Type experienced hyperglycemia (blood >10 mmol·L−1) as much 8:16 h:min (6:44 9:48 h:min) per day. The prevalence was reduced 31% 5:38 (3:17 7:00 (P < 0.001). lowered average blood concentrations 0.9 mmol·L−1 (0.7 1.2) variability 0.05). response showed considerable variation between subjects correlated positively with levels (r 0.38, P 0.01). Nevertheless, even well-controlled an level below 7.0% (n 28) achieved 28% reduction daily Conclusions A substantially improves throughout day insulin- non–insulin-treated Of only is magnitude exercise. present study demonstrates that benefit considerably from glucose-lowering properties