Coronavirus Disease 2019 and Kidney Transplantation in Saudi Arabia: Outcomes and Future Opportunities

• DOI: 10.12659/aot.931832
• Publication Date: 2021-05-13T14:10:20Z
• Authors: Ali Alshaqaq; Abdulnaser Al Abadi; Abdulrahman Altheaby; Mohammed A. Bukhari; Basil Alnasrallah; Alaa Alamoudi; Ziad Arabi; Fayez Alhejaili; Khalid Bin Saad; Ahmed Busbaih; Mohammed Abdelrah...; Sumayah Askandarani; Meteb M. AlBugami; Fahad E. Alotaibe; Khaled Hamawi; Khalid Bel’eed Ak...
• Keywords: Adult; Male; Original Paper; Saudi Arabia; COVID-19; Middle Aged; Kidney Transplantation; Telemedicine; Virus Shedding; 3. Good health; Cohort Studies; Hospitalization; Renal Replacement Therapy; 03 medical and health sciences; 0302 clinical medicine; Humans; Kidney Failure, Chronic; Female

BACKGROUND:Kidney transplant services all over the world were severely impacted by coronavirus disease 2019 pandemic. The optimum management of kidney recipients with remains uncertain. MATERIAL AND METHODS:We conducted a multicenter cohort study infection in Saudi Arabia. Multivariable Cox regression analysis was used to predictors graft and patient outcomes at 28 days after diagnosis. RESULTS:We included 130 recipients, mean age 48.7(±14.4) years. Fifty-nine patients managed home daily follow-up utilizing dedicated clinic, while 71 (54.6%) required hospital admission. Acute injury occurred 35 (26.9%) patients. Secondary infections 38 (29.2%) SARS-CoV-2 antibodies testing carried out 84 patients, whom 70 tested positive for IgG and/or IgM. Fourteen died (10.8%). A multivariable showed that age, creatinine presentation, acute injury, use azithromycin significantly associated worse survival. Graft loss requiring renal replacement therapy development secondary infections. CONCLUSIONS:Despite having higher rate admission mortality compared general population, significant number them can be using telemedicine clinic. Most seem mount an antibody response following infection, it seen if they will have similar incoming vaccines.