Recent Advances in Endometrial Cancer

• DOI: 10.12688/f1000research.10020.1
• Publication Date: 2017-01-27T16:25:04Z
• Authors: Arthur-Quan Tran; Paola Gehrig
• Keywords: 0301 basic medicine; 03 medical and health sciences; Review; 3. Good health

Endometrial cancer is the most common gynecologic malignancy in the United States, with yearly rates continuing to increase. Most women present with early stage disease; however, advanced disease carries a grave prognosis. As a result, novel therapies are currently under investigation for the treatment of endometrial cancer. These advances include a better understanding of the genetic basis surrounding the development of endometrial cancer, novel surgical therapies, and new molecular targets for the treatment of this disease. This review explores the literature regarding these advancements in endometrial cancer.