Uptake of core outcome sets by clinical trialists in China: a protocol

• DOI: 10.12688/f1000research.139282.3
• Publication Date: 2024-07-17T13:40:05Z
• Authors: Ruijin Qiu; Xiaodan Fan; Wenhui Wang; Mike Clarke; Zhuo Chen; Shuling Liu; Paula Williamson; Hongcai Shang
• Keywords: Open peer review; Open Science

<ns3:p>Background The concept of core outcome sets (COS) has been introduced in China for about 10 years. In recent years, some Chinese researchers also committed to developing COS, though the majority COS are ongoing. However, there were more than 500 published research COMET database by 2020. extent availability top 25 diseases with highest burden is unknown. addition, uptake clinical trials these unknown, along knowledge, perceptions, and views trialist community on use relation choosing outcomes their research. Methods main disease will be identified. Then we search identify if ongoing or completed relevant A since 2012 would preferred one before analysis meets eligibility criteria. We extract scopes eligible including condition, population, interventions, outcomes. Clinical Trial Registry using names each that a COS. assess overlap scope between conduct an online survey semi-structured interviews knowledge perceptions among primary investigators included trials. Discussion This fill gaps China. Understanding trialists’knowledge may help dissemination application future. registration registered Core Outcome Measures Effectiveness: https://www.comet-initiative.org/Studies/Details/2563.</ns3:p>